The Poison Lab

Episode #5- Toxicologists vs The Internet (#1) With Guest Dr. Matthew Stanton PharmD, DABAT

Episode Summary

In this episode Ryan Is joined by a special guest Dr. Matthew Stanton PharmD, BCPS, DABAT, an emergency medicine pharmacist and clinical toxicologist. Ryan and Matt take turns answering questions from reddit.com/r/askdrugs (the internet, really, really needs a toxicologist) and finally they challenge each others toxic sleuthing by presenting some cases of poisoning and allowing the other to try to determine the toxin responsible.

Episode Notes

• Article authored by Ryan and Matt regarding potential toxicity of vitamin e acetate in THC vape cartridges
  • https://pubmed.ncbi.nlm.nih.gov/32451600/
  • https://pubmed.ncbi.nlm.nih.gov/33528766/
• News article about the man arrested 1 floor below our Host where co-author of above paper is quouted. for selling vape cartridges
  • https://www.jsonline.com/story/news/2019/08/29/vaping-deaths-thc-cartridges-investigated-wisconsin-cases/2154799001/
• False Positive for Fentanyl
  • https://pubmed.ncbi.nlm.nih.gov/25248490/
• Serotonin syndrome
  • Great review of serotonin syndrome
    • https://pubmed.ncbi.nlm.nih.gov/15784664/
  • LSD Partial agonism at 5HT2A
    • https://pubmed.ncbi.nlm.nih.gov/8819525/
  • Review containing 5HT2A binding affinity for pyschoactive compounds
    • https://pubmed.ncbi.nlm.nih.gov/27216487/
  • Discussion of some cases of LSD related deaths
    • https://pubmed.ncbi.nlm.nih.gov/29408722/
  • Review of risk of serotonin syndrome with stimulant compounds
    • https://pubmed.ncbi.nlm.nih.gov/17620161/
  • Case report of methamphetamine serotonin syndrome
    • https://www.longdom.org/open-access/serotonin-syndrome-following-single-ingestion-of-high-dose-methamphetamine-2161-0495.1000111.pdf
• Cases
  • Review of toxicity from poison case 1
    • https://pubmed.ncbi.nlm.nih.gov/21739343/
  • Review of methemoglobinemia (case)
    • https://pubmed.ncbi.nlm.nih.gov/22024786/
  • Review of case 3 poison toxicity
    • https://pubmed.ncbi.nlm.nih.gov/21731786/
  • Case report of case 4 poisoning
    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130147/