Episode 30

Bromazolam, Etonitazene, and Carfentanil Walk into a Bar – Trends in Novel Illicit Drugs with Dr. Alex Krotulski

In this episode Ryan interviews Dr. Alex Krotulski PhD from the Center for Forensic Science Research and Education. Together take a look at trends in novel opioids, benzodiazepines, stimulants, hallucinogens, synthetic cannabinoids, and "hemp products" that are showing up in your patients, drug products, and fatal overdoses. The conversation takes places around the Center for Forensic Science Research and Education quarterly report on Novel Psychoactive Substances found in patients and drug products.

 

The episode starts with a discussion of the novel benzodiazepines market, highlighting bromazolam and how long it may remain in the market. Then they discuss the opioids highlighting where we are seeing carfentanil, what is happening with Para Fluorofentanyl, and other super potent opioids emergening (such as  N -pyrrolidino etonitazene). After a quick discussion of synthetic cathinone's and PCP/ketamine derivatives they jump to synthetic cannabinoids, examining the history of brodifacoum contamination and how regulation has led to market changes. 

 

  1. Resources
  2. https://www.cfsre.org/
  3. Quarterly report  discussed on this episode
  4. More on Dr. Krotulski
  5. Poster from Dr. Kortulksi on naming conventions for NPS
  6. Time stamps to jump to any portion of the episode you want to revisit
  7. Introduction-5:00-32:50
  • 06:30-25:16- Discussion CSFRE mission, history of NPS reports, and other available reports
  • 25:14- "Miscellaneous drugs: Furanyl UF17, medetomidine"
  • 28:15- Difference between GC/MS and LCqTOF
  1. Novel Benzodiazepines- 32:50
  2. Novel Opioids-43:00
  3. Stimulants and hallucinogens- 1:01:43
  4. Synthetic cannabinoids- 1:07:40
  5. Novel psychedelics markets, hemp products, phenibut, tianeptine, and kratom-1:25:12

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About the Podcast

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The Poison Lab
Explore the world of poisoning with Clinical Toxicologist Ryan Feldman and Cohost Toxo, dive into the history, science, and life-saving care of poisoning. Survivor stories, expert insights, and deep dives—every poison has a story to tell!

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Ryan Feldman

Dr. Ryan Feldman PharmD, DABAT is the chief scientist at The Poison Lab. He works as a Clinical Toxicologist, Emergency Medicine Pharmacist, and Clinical Assistant Professor of Pharmacy and Emergency medicine.

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